Skin Biorevitalisation Milan
Hyaluronic Acid and Skin Boosters with Dr. Alice Miegge
Skin biorevitalisation is an injectable treatment that delivers non-cross-linked hyaluronic acid, vitamins and amino acids directly into the dermis to restore deep skin hydration and stimulate the skin's natural production of collagen and elastin. The full course involves 2–3 sessions spaced 3–4 weeks apart, with results visible from the first session.

What is Skin Biorevitalisation Milan?
Skin biorevitalisation is an injectable treatment that delivers non-cross-linked hyaluronic acid, vitamins and amino acids directly into the dermis to restore deep skin hydration and stimulate the skin's natural production of collagen and elastin. The full course involves 2–3 sessions spaced 3–4 weeks apart, with results visible from the first session.
Skin biorevitalisation is the go-to treatment when the goal is to improve skin quality from within, working on its deep structure rather than on volume or expression. In Dr. Alice Miegge’s regenerative philosophy, it’s often the first step of a skincare journey or the maintenance treatment between more structured sessions.
Deep hydration vs surface hydration
Dehydrated skin doesn’t respond to topical cosmetic products as effectively as one might hope, because these only act on the surface layers of the epidermis. Injectable biorevitalisation delivers hyaluronic acid directly into the dermis, where the molecule retains water up to 1000 times its own weight and stimulates fibroblasts to produce new collagen and elastin.
The result is plumper, more radiant, firmer skin that stays that way over time — not simply hydrated on the surface for a few hours.
The products used
Dr. Miegge selects the product based on the patient’s skin characteristics and goals. For heavily dehydrated, lacklustre skin, she favours vitamin cocktails enriched with amino acids, coenzymes and antioxidants. For skin with loss of tone and elasticity, she uses high-concentration hybrid hyaluronic acid or amino acid and hyaluronic acid complexes, intended for a more structural action on the dermal matrix.
An ideal treatment in combination
Biorevitalisation integrates perfectly with fractional lasers, chemical peels and dermal fillers, amplifying their results and speeding up skin recovery. It’s often the recommended preparation treatment before a laser session, or the maintenance care in the following months.
How the treatment works
- 1
Assessment of skin type and hydration level
Dr. Miegge assesses skin condition, degree of dehydration and loss of tone to select the most suitable product among free hyaluronic acid, high-concentration hybrid hyaluronic acid, amino acid and hyaluronic acid complexes or personalised vitamin cocktails.
- 2
Cleansing and skin preparation
The area to be treated is carefully cleansed and, on request, a topical anaesthetic cream is applied 20–30 minutes before treatment.
- 3
Intradermal injections using nappage or microbolus technique
The product is injected superficially into the dermis using the nappage technique (multiple closely spaced injections) or microbolus, depending on the protocol. For hybrid hyaluronic acid, a 5-points-per-side protocol is generally used.
- 4
Distribution massage
After the injections, a gentle massage is performed to help distribute the product evenly and reduce localised swelling at the injection points.
- 5
Assessment and course planning
The next session is scheduled 3–4 weeks later. A full biorevitalisation course usually involves 2–3 sessions, followed by a maintenance session every 4–6 months.
Who it's suitable for
Dehydrated, dull skin lacking radiance
Skin with loss of tone and elasticity
Superficial wrinkles from dehydration
Skin damaged by chronic sun exposure
Preparation before events or the summer season
Maintenance after laser treatments or peels
Neck, décolletage and hands showing signs of skin ageing
Skin recovering after pregnancy
Expected results
- ✓Visibly brighter, more hydrated skin from the first session
- ✓Improved skin texture and reduced surface roughness
- ✓Increased skin tone and elasticity after the full course
- ✓Softening of superficial dehydration wrinkles
- ✓Firmer-looking skin with high-concentration hybrid hyaluronic acid
- ✓Stimulation of the skin's own collagen and elastin production
- ✓Optimal results maintained for 4–6 months with a follow-up session
Clinical data
The Specialist
Dr. Alice Miegge
Surgeon specialised in General Surgery, with a Master's Degree in Aesthetic Medicine and Laser Therapy (University of Pavia). Fellowship at Imperial College NHS Trust, London. Author of 15+ international scientific publications.
Frequently Asked Questions
Fillers contain cross-linked (thickened) hyaluronic acid and are used to restore volume and structure in specific areas. Biorevitalisation uses non-cross-linked or hybrid hyaluronic acid, which spreads through the dermis improving hydration, tone and elasticity overall without adding volume.
It is a non-cross-linked hyaluronic acid in which chains of different molecular weights are stabilised together. It spreads through the dermis with a hydrating and biostimulating action. It is generally injected at 5 points per side, with a progressive effect over the following weeks that varies from person to person.
A full course usually involves 2–3 sessions spaced 3–4 weeks apart. Results improve progressively over the course. For maintenance, a session every 4–6 months is recommended.
Yes. In younger patients (25–35 years) it's indicated as a preventive treatment to slow down signs of skin ageing. In more mature patients it's useful for restoring hydration, tone and radiance. The protocol is personalised based on age and skin condition.
Yes. Biorevitalisation is particularly effective for the neck, décolletage and hands — areas often neglected that show early signs of skin ageing. The treatment can be performed in combination with the face in the same session.
Contact Dr. Miegge
Dr. Alice Miegge practises at Image Regenerative Clinic in Milan (San Babila area) and YouMedical in Seregno. A consultation is the first step towards a personalised treatment plan.